«A new study of the effects of a new antibody treatment suggests it may offer a long-term solution for the control of HIV.
The results of the trial suggest that the antibody therapy not only
exerts pressure on blood levels of the virus and stops it infecting new
immune cells, but it may also shorten the survival of infected cells.
There is no doubt that antiretroviral therapy (ART) for HIV has transformed what used to be a death sentence into a chronic condition, allowing infected people to live decades longer.
There is no doubt that antiretroviral therapy (ART) for HIV has transformed what used to be a death sentence into a chronic condition, allowing infected people to live decades longer.
But ART has its drawbacks, not only in terms of physical side effects
such as decreased bone density and kidney problems, but also in that
stopping treatment or just missing a few doses causes the virus to
resurge.
The new study, published in the journal Science, concerns a different and potentially superior approach, in the form of a lasting immunotherapy that triggers an infected person's immune system to make antibodies against HIV and clear it from the body.
Dr. Till Schoofs, one of the study's first authors, and a researcher in molecular immunology at Rockefeller University in New York, NY, says:
"This study provides evidence that a single dose of an antibody stimulates patients' immune response, enabling them to make new or better antibodies against the virus."
Last year, the team reported that the same treatment, based on a molecule called 3BNC117, can greatly reduce the amount of virus present in a patient's blood.»
Fonte: http://www.medicalnewstoday.com/articles/310065.php
Comentário do Bloguista: Este estudo vem promover desenvolvimento de estratégias terapêuticas cada vez mais eficazes no tratamento de um vírus tão bem conhecido relativamente ao seu impacto na saúde mundial. Com recurso à imunoterapia, estabelece-se a possibilidade da promoção de um efeito anti-viral cada vez mais potente, exercendo também um efeito na diminuição da sobrevivência das células infetadas.
The new study, published in the journal Science, concerns a different and potentially superior approach, in the form of a lasting immunotherapy that triggers an infected person's immune system to make antibodies against HIV and clear it from the body.
Dr. Till Schoofs, one of the study's first authors, and a researcher in molecular immunology at Rockefeller University in New York, NY, says:
"This study provides evidence that a single dose of an antibody stimulates patients' immune response, enabling them to make new or better antibodies against the virus."
Last year, the team reported that the same treatment, based on a molecule called 3BNC117, can greatly reduce the amount of virus present in a patient's blood.»
Fonte: http://www.medicalnewstoday.com/articles/310065.php
Comentário do Bloguista: Este estudo vem promover desenvolvimento de estratégias terapêuticas cada vez mais eficazes no tratamento de um vírus tão bem conhecido relativamente ao seu impacto na saúde mundial. Com recurso à imunoterapia, estabelece-se a possibilidade da promoção de um efeito anti-viral cada vez mais potente, exercendo também um efeito na diminuição da sobrevivência das células infetadas.
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